Entity Details

Primary name PTGES_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14684
EntryNamePTGES_HUMAN
FullNameProstaglandin E synthase
TaxID9606
Evidenceevidence at protein level
Length152
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPTGES

GO terms

Show/Hide Table
GOName
GO:0001516 prostaglandin biosynthetic process
GO:0002526 acute inflammatory response
GO:0002544 chronic inflammatory response
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0004667 prostaglandin-D synthase activity
GO:0005641 nuclear envelope lumen
GO:0005789 endoplasmic reticulum membrane
GO:0006693 prostaglandin metabolic process
GO:0007165 signal transduction
GO:0008285 negative regulation of cell population proliferation
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019233 sensory perception of pain
GO:0019371 cyclooxygenase pathway
GO:0031620 regulation of fever generation
GO:0032308 positive regulation of prostaglandin secretion
GO:0032496 response to lipopolysaccharide
GO:0032526 response to retinoic acid
GO:0034097 response to cytokine
GO:0043295 glutathione binding
GO:0048471 perinuclear region of cytoplasm
GO:0050220 prostaglandin-E synthase activity
GO:0050727 regulation of inflammatory response
GO:0051592 response to calcium ion

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) proteinFamilyFamily
IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamilyFamilyHomologous superfamily
IPR040162 Microsomal glutathione S-transferase 1-likeFamilyFamily

Diseases

Show/Hide Table