Entity Details

Primary name MTMR8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96EF0
EntryNameMTMR8_HUMAN
FullNameMyotubularin-related protein 8
TaxID9606
Evidenceevidence at protein level
Length704
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesMTMR8

GO terms

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GOName
GO:0004438 phosphatidylinositol-3-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006661 phosphatidylinositol biosynthetic process
GO:0010507 negative regulation of autophagy
GO:0016241 regulation of macroautophagy
GO:0032991 protein-containing complex
GO:0046856 phosphatidylinositol dephosphorylation
GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity

Subcellular Location

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Subcellular Location
Nucleus envelope

Domains

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DomainNameCategoryType
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR010569 Myotubularin-like phosphatase domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR030564 Myotubularin familyFamilyFamily
IPR030591 Myotubularin-related protein 8FamilyFamily

Diseases

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Interactions

3 interactions