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Entity Details
Primary name
PGAM5_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96HS1
EntryName
PGAM5_HUMAN
FullName
Serine/threonine-protein phosphatase PGAM5, mitochondrial
TaxID
9606
Evidence
evidence at protein level
Length
289
SequenceStatus
complete
DateCreated
2007-05-29
DateModified
2021-06-02
Ontological Relatives
Genes
PGAM5
GO terms
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GO
Name
GO:0004722
protein serine/threonine phosphatase activity
GO:0005096
GTPase activator activity
GO:0005739
mitochondrion
GO:0005741
mitochondrial outer membrane
GO:0016021
integral component of membrane
GO:0016236
macroautophagy
GO:0016791
phosphatase activity
GO:0044877
protein-containing complex binding
GO:0070266
necroptotic process
GO:0106306
protein serine phosphatase activity
GO:0106307
protein threonine phosphatase activity
GO:0120163
negative regulation of cold-induced thermogenesis
Subcellular Location
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Subcellular Location
Mitochondrion outer membrane
Domains
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Domain
Name
Category
Type
IPR013078
Histidine phosphatase superfamily, clade-1
Family
Family
IPR029033
Histidine phosphatase superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
25 interactions
Interactor
Partner
Sources
Publications
Link
PGAM5_HUMAN
ZBT16_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PGAM5_HUMAN
HS71A_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PGAM5_HUMAN
HS71B_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PGAM5_HUMAN
SETB1_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PGAM5_HUMAN
PGAM5_HUMAN
BioGRID, IntAct
22265414
27218139
details
PGAM5_HUMAN
PINK1_HUMAN
BioGRID
21151955
31177901
details
PGAM5_HUMAN
XIAP_HUMAN
BioGRID
23201124
details
PGAM5_HUMAN
BIRC2_HUMAN
BioGRID
23201124
details
PGAM5_HUMAN
UBE4B_HUMAN
BioGRID
29326975
details
PGAM5_HUMAN
RNPS1_HUMAN
IntAct
17353931
details
PGAM5_HUMAN
KEAP1_HUMAN
BioGRID, IntAct
17046835
18387606
19615732
28416489
30126895
details
PGAM5_HUMAN
PHS_HUMAN
IntAct
20195357
details
PGAM5_HUMAN
DNM1L_HUMAN
IntAct
22265414
details
PGAM5_HUMAN
CUL3_HUMAN
BioGRID, IntAct
17046835
21145461
details
PGAM5_HUMAN
M3K5_HUMAN
DIP
19590015
details
PGAM5_HUMAN
AIFM1_HUMAN
BioGRID, IntAct
27218139
29568061
34079125
details
PGAM5_HUMAN
MAVS_HUMAN
MINT
32433485
details
PGAM5_HUMAN
B2CL1_HUMAN
BioGRID
17046835
details
PGAM5_HUMAN
RBX1_HUMAN
BioGRID
17046835
details
PGAM5_HUMAN
HDAC5_HUMAN
BioGRID
21081666
details
PGAM5_HUMAN
NF2L2_HUMAN
BioGRID
18387606
details
PGAM5_HUMAN
GLI1_HUMAN
BioGRID
26603838
details
PGAM5_HUMAN
PHB2_HUMAN
BioGRID
31177901
31536960
34079125
details
PGAM5_HUMAN
PHB_HUMAN
BioGRID
31177901
details
PGAM5_HUMAN
1433G_HUMAN
HPRD
15324660
details
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