Entity Details

Primary name KCNC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PR1
EntryNameKCNC2_HUMAN
FullNamePotassium voltage-gated channel subfamily C member 2
TaxID9606
Evidenceevidence at protein level
Length638
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesKCNC2

GO terms

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GOName
GO:0001508 action potential
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0009642 response to light intensity
GO:0014070 response to organic cyclic compound
GO:0014075 response to amine
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0021759 globus pallidus development
GO:0030424 axon
GO:0030425 dendrite
GO:0030673 axolemma
GO:0031982 vesicle
GO:0032026 response to magnesium ion
GO:0032590 dendrite membrane
GO:0032809 neuronal cell body membrane
GO:0038060 nitric oxide-cGMP-mediated signaling pathway
GO:0042734 presynaptic membrane
GO:0043195 terminal bouton
GO:0043204 perikaryon
GO:0044325 transmembrane transporter binding
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045471 response to ethanol
GO:0050796 regulation of insulin secretion
GO:0051260 protein homooligomerization
GO:0051291 protein heterooligomerization
GO:0071242 cellular response to ammonium ion
GO:0071732 cellular response to nitric oxide
GO:0071805 potassium ion transmembrane transport
GO:0097237 cellular response to toxic substance
GO:0099508 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:1903818 positive regulation of voltage-gated potassium channel activity
GO:1990089 response to nerve growth factor

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell junction
Cell membrane
Cell projection
Membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003974 Potassium channel, voltage dependent, Kv3FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
KCNC2_HUMANKCNC1_HUMANBioGRID12805291 details