Entity Details

Primary name ALS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96Q42
EntryNameALS2_HUMAN
FullNameAlsin
TaxID9606
Evidenceevidence at protein level
Length1657
SequenceStatuscomplete
DateCreated2003-05-09
DateModified2021-06-02

Ontological Relatives

GenesALS2

GO terms

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GOName
GO:0001726 ruffle
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005813 centrosome
GO:0005829 cytosol
GO:0007032 endosome organization
GO:0007041 lysosomal transport
GO:0030027 lamellipodium
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031267 small GTPase binding
GO:0031982 vesicle
GO:0032991 protein-containing complex
GO:0035022 positive regulation of Rac protein signal transduction
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043539 protein serine/threonine kinase activator activity
GO:0043547 positive regulation of GTPase activity
GO:0045860 positive regulation of protein kinase activity
GO:0048812 neuron projection morphogenesis
GO:0051036 regulation of endosome size
GO:0051260 protein homooligomerization

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000408 Regulator of chromosome condensation, RCC1RepeatRepeat
IPR003123 VPS9 domainDomainDomain
IPR003409 MORN motifRepeatRepeat
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR037191 VPS9 domain superfamilyFamilyHomologous superfamily

Diseases

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