Entity Details

Primary name SPTN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15020
EntryNameSPTN2_HUMAN
FullNameSpectrin beta chain, non-erythrocytic 2
TaxID9606
Evidenceevidence at protein level
Length2390
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesSPTBN2

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005543 phospholipid binding
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0008091 spectrin
GO:0016192 vesicle-mediated transport
GO:0016324 apical plasma membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0021692 cerebellar Purkinje cell layer morphogenesis
GO:0030534 adult behavior
GO:0035264 multicellular organism growth
GO:0043025 neuronal cell body
GO:0045296 cadherin binding
GO:0051693 actin filament capping
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0098793 presynapse
GO:0098918 structural constituent of synapse
GO:0098978 glutamatergic synapse
GO:0099173 postsynapse organization
GO:0099189 postsynaptic spectrin-associated cytoskeleton

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001605 Pleckstrin homology domain, spectrin-typeDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016343 Spectrin, beta subunitFamilyFamily
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036872 CH domain superfamilyFamilyHomologous superfamily
IPR041681 Pleckstrin homology domain 9DomainDomain

Diseases

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