Entity Details

Primary name CYH2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99418
EntryNameCYH2_HUMAN
FullNameCytohesin-2
TaxID9606
Evidenceevidence at protein level
Length400
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCYTH2

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0006897 endocytosis
GO:0008289 lipid binding
GO:0016020 membrane
GO:0030036 actin cytoskeleton organization
GO:0030426 growth cone
GO:0032012 regulation of ARF protein signal transduction
GO:0070679 inositol 1,4,5 trisphosphate binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000904 Sec7 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR023394 Sec7, C-terminal domain superfamilyFamilyHomologous superfamily
IPR035999 Sec7 domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01863 Inositol 1,3,4,5-TetrakisphosphateDrugbanksmall molecule
DB01942 Formic acidDrugbanksmall molecule
DB03401 1D-myo-inositol 1,4,5-trisphosphateDrugbanksmall molecule
DB04530 S,S-(2-Hydroxyethyl)ThiocysteineDrugbanksmall molecule
DB07348 Brefeldin ADrugbanksmall molecule

Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
CYH2_HUMANARF1_HUMANBioGRID, DIP, HPRD, IntAct10198630 14654833 17563369 9417041 details
CYH2_HUMANCC120_HUMANBioGRID, HPRD, IntAct16189514 25416956 28514442 29892012 32296183 details
CYH2_HUMANVPP2_HUMANBioGRID, HPRD, IntAct16415858 21307348 details
CYH2_HUMANGRB2_HUMANIntAct17474147 details
CYH2_HUMANAA2AR_HUMANBioGRID, HPRD, IntAct16027149 details
CYH2_HUMANAPC_HUMANBioGRID, IntAct20936779 details
CYH2_HUMANMK06_HUMANBioGRID, MINT21900206 details
CYH2_HUMANICEF1_HUMANBioGRID, HPRD, IntAct12920129 28514442 32296183 details
CYH2_HUMANCNKR1_HUMANBioGRID, IntAct28514442 32296183 details
CYH2_HUMANARF6_HUMANBioGRID, HPRD, IntAct17846866 18094045 27265506 9417041 details
CYH2_HUMANINAVA_HUMANBioGRID, DIP, IntAct28514442 29420262 30355448 details
CYH2_HUMANARRB1_HUMANBioGRID, HPRD11533043 details
CYH2_HUMANARRB2_HUMANBioGRID, HPRD11533043 details
CYH2_HUMANTRI23_HUMANBioGRID, HPRD10748148 details
CYH2_HUMANPLPL2_HUMANBioGRID21789191 details
CYH2_HUMANGNAQ_HUMANBioGRID16650966 details
CYH2_HUMANPK3CA_HUMANBioGRID21041639 details
CYH2_HUMANARL4D_HUMANBioGRID17804820 details
CYH2_HUMANARL4A_HUMANBioGRID17804820 details
CYH2_HUMANGGA3_HUMANBioGRID17804820 details
CYH2_HUMANALDOA_HUMANBioGRID21307348 details
CYH2_HUMANVPP1_HUMANBioGRID21307348 details
CYH2_HUMANVPP3_HUMANBioGRID21307348 details
CYH2_HUMANVPP4_HUMANBioGRID21307348 details
CYH2_HUMANDOCK1_HUMANBioGRID20016009 details
CYH2_HUMANCUX1_HUMANHPRD12052827 details
CYH2_HUMANITB2_HUMANHPRD8706128 details
CYH2_HUMAN1433S_HUMANBioGRID, MINT15778465 details
CYH2_HUMANCYTIP_HUMANBioGRID, HPRD, IntAct12606567 26186194 28514442 details
CYH2_HUMANMYD88_HUMANBioGRID, DIP23143332 details
CYH2_HUMANKPCA_HUMANHPRD10531036 details
CYH2_HUMANKPCB_HUMANHPRD10531036 details
CYH2_HUMANKPCG_HUMANHPRD10531036 details
CYH2_HUMANARFG1_HUMANHPRD9476900 details