Entity Details

Primary name LGMN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99538
EntryNameLGMN_HUMAN
FullNameLegumain
TaxID9606
Evidenceevidence at protein level
Length433
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesLGMN

GO terms

Show/Hide Table
GOName
GO:0002224 toll-like receptor signaling pathway
GO:0003014 renal system process
GO:0004197 cysteine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005770 late endosome
GO:0006508 proteolysis
GO:0006624 vacuolar protein processing
GO:0007613 memory
GO:0008233 peptidase activity
GO:0008284 positive regulation of cell population proliferation
GO:0008306 associative learning
GO:0010447 response to acidic pH
GO:0010629 negative regulation of gene expression
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0032801 receptor catabolic process
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0036021 endolysosome lumen
GO:0040015 negative regulation of multicellular organism growth
GO:0042359 vitamin D metabolic process
GO:0043202 lysosomal lumen
GO:0043524 negative regulation of neuron apoptotic process
GO:0045177 apical part of cell
GO:0045931 positive regulation of mitotic cell cycle
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0070062 extracellular exosome
GO:0071277 cellular response to calcium ion
GO:0090026 positive regulation of monocyte chemotaxis
GO:0097061 dendritic spine organization
GO:0097202 activation of cysteine-type endopeptidase activity
GO:0097264 self proteolysis
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1901185 negative regulation of ERBB signaling pathway
GO:1904646 cellular response to amyloid-beta
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

Show/Hide Table
Subcellular Location
Lysosome

Domains

Show/Hide Table
DomainNameCategoryType
IPR001096 Peptidase C13, legumainFamilyFamily
IPR043577 Asparaginyl endopeptidaseFamilyFamily

Diseases

Show/Hide Table