Entity Details

Primary name MGST2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99735
EntryNameMGST2_HUMAN
FullNameMicrosomal glutathione S-transferase 2
TaxID9606
Evidenceevidence at protein level
Length147
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesMGST2

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0004464 leukotriene-C4 synthase activity
GO:0004602 glutathione peroxidase activity
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006629 lipid metabolic process
GO:0006750 glutathione biosynthetic process
GO:0008047 enzyme activator activity
GO:0010243 response to organonitrogen compound
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019370 leukotriene biosynthetic process
GO:0032496 response to lipopolysaccharide
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043295 glutathione binding
GO:0046222 aflatoxin metabolic process
GO:0046466 membrane lipid catabolic process
GO:0050729 positive regulation of inflammatory response
GO:1901687 glutathione derivative biosynthetic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) proteinFamilyFamily
IPR001446 5-lipoxygenase-activating proteinFamilyFamily
IPR018295 FLAP/GST2/LTC4S, conserved siteSiteConserved site
IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB01008 BusulfanSwissprotsmall molecule