Entity Details

Primary name BBS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXC9
EntryNameBBS2_HUMAN
FullNameBardet-Biedl syndrome 2 protein
TaxID9606
Evidenceevidence at protein level
Length721
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesBBS2

GO terms

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GOName
GO:0005829 cytosol
GO:0005902 microvillus
GO:0007288 sperm axoneme assembly
GO:0007601 visual perception
GO:0008104 protein localization
GO:0010629 negative regulation of gene expression
GO:0014824 artery smooth muscle contraction
GO:0016020 membrane
GO:0021756 striatum development
GO:0021766 hippocampus development
GO:0021987 cerebral cortex development
GO:0030534 adult behavior
GO:0031514 motile cilium
GO:0032402 melanosome transport
GO:0032420 stereocilium
GO:0033365 protein localization to organelle
GO:0034464 BBSome
GO:0036064 ciliary basal body
GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway
GO:0040015 negative regulation of multicellular organism growth
GO:0040018 positive regulation of multicellular organism growth
GO:0042311 vasodilation
GO:0043001 Golgi to plasma membrane protein transport
GO:0043005 neuron projection
GO:0045444 fat cell differentiation
GO:0045494 photoreceptor cell maintenance
GO:0048854 brain morphogenesis
GO:0051216 cartilage development
GO:0060170 ciliary membrane
GO:0060271 cilium assembly
GO:0060296 regulation of cilium beat frequency involved in ciliary motility
GO:1905515 non-motile cilium assembly

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016616 Bardet-Biedl syndrome 2 proteinFamilyFamily
IPR029333 Ciliary BBSome complex subunit 2, C-terminal domainDomainDomain
IPR029429 Ciliary BBSome complex subunit 2, middle regionDomainDomain
IPR029430 Ciliary BBSome complex subunit 2, N-terminalDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
BBS2_HUMANPSME3_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
BBS2_HUMANACY1_HUMANIntAct18000879 details
BBS2_HUMANALDOB_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANBHMT1_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANEF1A1_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANEPAS1_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANEXOC7_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANFHOD1_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANFLOT1_HUMANIntAct18000879 details
BBS2_HUMANHSC20_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANK1C18_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANPAX2_HUMANBioGRID, IntAct18000879 details
BBS2_HUMANPCM1_HUMANIntAct18000879 details
BBS2_HUMANPTHB1_HUMANBioGRID, DIP, IntAct17574030 20080638 22139371 22500027 27173435 29039417 unassigned1312 details
BBS2_HUMANBBS7_HUMANBioGRID, DIP, IntAct17574030 20080638 22500027 27173435 28514442 29039417 unassigned1312 details
BBS2_HUMANRBPMS_HUMANBioGRID, IntAct25416956 details
BBS2_HUMANMDFI_HUMANBioGRID, IntAct25416956 32296183 details
BBS2_HUMANFND3B_HUMANBioGRID, IntAct32296183 details
BBS2_HUMANNRF1_HUMANBioGRID, IntAct32296183 details
BBS2_HUMANHNRPF_HUMANBioGRID, IntAct32296183 details
BBS2_HUMANLMO4_HUMANBioGRID, IntAct32296183 details
BBS2_HUMANBBS4_HUMANBioGRID, IntAct, UniProt17574030 19081074 22139371 22500027 25552655 27173435 unassigned1312 details
BBS2_HUMANBBS1_HUMANBioGRID, IntAct17574030 22500027 27173435 28514442 unassigned1312 details
BBS2_HUMANTTC8_HUMANBioGRID, IntAct22139371 22500027 27173435 unassigned1312 details
BBS2_HUMANBBS5_HUMANBioGRID, DIP, IntAct, UniProt20080638 22500027 25552655 27173435 28514442 unassigned1312 details
BBS2_HUMANTCPB_HUMANIntAct22500027 details
BBS2_HUMANMKKS_HUMANDIP, IntAct20080638 22500027 details
BBS2_HUMANLZTL1_HUMANBioGRID, IntAct22072986 26186194 27173435 28514442 unassigned1312 details
BBS2_HUMANC2CD3_HUMANIntAct24997988 details
BBS2_HUMANRFOX1_HUMANBioGRID, IntAct27173435 unassigned1312 details
BBS2_HUMANPCKGM_HUMANBioGRID, IntAct27173435 unassigned1312 details
BBS2_HUMANCLUA1_HUMANBioGRID, IntAct27173435 29615496 unassigned1312 details
BBS2_HUMANIQCB1_HUMANUniProt25552655 details
BBS2_HUMANCE290_HUMANUniProt25552655 details
BBS2_HUMANCC28B_HUMANDIP16327777 details
BBS2_HUMANBBS12_HUMANDIP20080638 details
BBS2_HUMANDISC1_HUMANIntAct31413325 details
BBS2_HUMANGLIS2_HUMANBioGRID24500717 details