Entity Details

Primary name AGT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BYV1
EntryNameAGT2_HUMAN
FullNameAlanine--glyoxylate aminotransferase 2, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length514
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesAGXT2

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0008453 alanine-glyoxylate transaminase activity
GO:0009436 glyoxylate catabolic process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
GO:0019481 L-alanine catabolic process, by transamination
GO:0030170 pyridoxal phosphate binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046487 glyoxylate metabolic process
GO:0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR005814 Aminotransferase class-IIIFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00119 Pyruvic acidDrugbanksmall molecule
DB00145 GlycineDrugbanksmall molecule
DB00160 AlanineDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AGT2_HUMANALDOB_HUMANBioGRID, IntAct21988832 details
AGT2_HUMANCP2E1_HUMANBioGRID, IntAct21988832 details