Entity Details

Primary name SC5A7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9GZV3
EntryNameSC5A7_HUMAN
FullNameHigh affinity choline transporter 1
TaxID9606
Evidenceevidence at protein level
Length580
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesSLC5A7

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0005307 choline:sodium symporter activity
GO:0005886 plasma membrane
GO:0006836 neurotransmitter transport
GO:0007271 synaptic transmission, cholinergic
GO:0007274 neuromuscular synaptic transmission
GO:0008292 acetylcholine biosynthetic process
GO:0015220 choline transmembrane transporter activity
GO:0015871 choline transport
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0031594 neuromuscular junction
GO:0033265 choline binding
GO:0043204 perikaryon
GO:0045202 synapse
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR001734 Sodium/solute symporterFamilyFamily
IPR038377 Sodium/glucose symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00122 CholineDrugbanksmall molecule
DB14006 Choline salicylateDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SC5A7_HUMANS14L1_HUMANBioGRID17092608 details
SC5A7_HUMANPAWR_HUMANBioGRID, HPRD15090548 details
SC5A7_HUMANNEDD4_HUMANBioGRID22361880 details