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Entity Details
Primary name
APC1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9H1A4
EntryName
APC1_HUMAN
FullName
Anaphase-promoting complex subunit 1
TaxID
9606
Evidence
evidence at protein level
Length
1944
SequenceStatus
complete
DateCreated
2003-10-03
DateModified
2021-06-02
Ontological Relatives
Genes
ANAPC1
GO terms
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GO
Name
GO:0005654
nucleoplasm
GO:0005680
anaphase-promoting complex
GO:0005829
cytosol
GO:0006511
ubiquitin-dependent protein catabolic process
GO:0007091
metaphase/anaphase transition of mitotic cell cycle
GO:0007096
regulation of exit from mitosis
GO:0031145
anaphase-promoting complex-dependent catabolic process
GO:0051301
cell division
GO:0060090
molecular adaptor activity
GO:0070979
protein K11-linked ubiquitination
GO:1901990
regulation of mitotic cell cycle phase transition
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR024990
Anaphase-promoting complex subunit 1
Family
Family
IPR041221
Anaphase-promoting complex subunit 1, C-terminal
Domain
Domain
Diseases
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Drugs
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Interactions
31 interactions
Interactor
Partner
Sources
Publications
Link
APC1_HUMAN
FZR1_HUMAN
BioGRID, IntAct
12956947
28514442
details
APC1_HUMAN
MDC1_HUMAN
BioGRID
17827148
19826003
22990118
details
APC1_HUMAN
FBX5_HUMAN
BioGRID
16921029
details
APC1_HUMAN
UBC_HUMAN
BioGRID
23314748
details
APC1_HUMAN
UBE2S_HUMAN
BioGRID
25306923
details
APC1_HUMAN
WBP2_HUMAN
BioGRID
27578003
details
APC1_HUMAN
RASH_HUMAN
BioGRID
30655611
details
APC1_HUMAN
SUMO2_HUMAN
BioGRID
32786267
details
APC1_HUMAN
CDC16_HUMAN
BioGRID, IntAct
11076961
20360068
22939629
26344197
26496610
28514442
details
APC1_HUMAN
CDC27_HUMAN
BioGRID, IntAct
11076961
12956947
16364912
17942546
20360068
20686030
21043528
22193957
22939629
26344197
27114510
32076268
32152539
details
APC1_HUMAN
BUB1B_HUMAN
BioGRID, IntAct
20360068
25482201
25852190
details
APC1_HUMAN
ANC2_HUMAN
BioGRID, DIP, IntAct
10922056
11076961
12956947
20360068
22939629
25043029
26083744
27120157
34079125
details
APC1_HUMAN
CDC20_HUMAN
BioGRID, HPRD, IntAct
11438673
18997788
20360068
24464857
25306918
25482201
26811472
26960431
27114510
28404789
details
APC1_HUMAN
APC7_HUMAN
BioGRID, IntAct
11076961
20360068
22939629
26344197
details
APC1_HUMAN
CDC23_HUMAN
BioGRID, IntAct
11076961
20360068
22939629
26496610
details
APC1_HUMAN
APC5_HUMAN
BioGRID, IntAct
11076961
12956947
20360068
22939629
26344197
details
APC1_HUMAN
APC4_HUMAN
BioGRID, DIP, IntAct
11076961
12956947
20360068
22939629
23078409
24464857
25043029
25490258
26083744
26344197
29549242
details
APC1_HUMAN
APC15_HUMAN
BioGRID, IntAct
23007861
26496610
details
APC1_HUMAN
MD2L1_HUMAN
BioGRID, IntAct
26496610
26986935
details
APC1_HUMAN
SMRCD_HUMAN
BioGRID
21549307
details
APC1_HUMAN
CSN2_HUMAN
BioGRID
19535905
details
APC1_HUMAN
TRI33_HUMAN
BioGRID
23160376
31753913
details
APC1_HUMAN
PHF8_HUMAN
BioGRID
23979597
details
APC1_HUMAN
LATS2_HUMAN
BioGRID
24255178
29183995
details
APC1_HUMAN
UBP1_HUMAN
BioGRID
21768287
details
APC1_HUMAN
SIR6_HUMAN
BioGRID
24169447
details
APC1_HUMAN
UBP15_HUMAN
BioGRID
26884171
details
APC1_HUMAN
LATS1_HUMAN
BioGRID
29183995
details
APC1_HUMAN
TNR6A_HUMAN
BioGRID
28813667
details
APC1_HUMAN
PP2AA_HUMAN
BioGRID
28404789
details
APC1_HUMAN
WDR5_HUMAN
BioGRID
32076268
details
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