Entity Details

Primary name YTDC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H6S0
EntryNameYTDC2_HUMAN
FullName3'-5' RNA helicase YTHDC2
TaxID9606
Evidenceevidence at protein level
Length1430
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesYTHDC2

GO terms

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GOName
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0007286 spermatid development
GO:0008186 ATPase, acting on RNA
GO:0034458 3'-5' RNA helicase activity
GO:0034612 response to tumor necrosis factor
GO:0035770 ribonucleoprotein granule
GO:0044829 positive regulation by host of viral genome replication
GO:0048471 perinuclear region of cytoplasm
GO:0048599 oocyte development
GO:0051321 meiotic cell cycle
GO:0051729 germline cell cycle switching, mitotic to meiotic cell cycle
GO:0070063 RNA polymerase binding
GO:0070555 response to interleukin-1
GO:1990247 N6-methyladenosine-containing RNA binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001374 R3H domainDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR007275 YTH domainDomainDomain
IPR007502 Helicase-associated domainDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR011709 Domain of unknown function DUF1605DomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031083 3'-5' RNA helicase YTHDC2-likeFamilyFamily
IPR034083 DExH-box ATP-dependent RNA helicase, R3H domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR036867 R3H domain superfamilyFamilyHomologous superfamily

Diseases

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