Entity Details

Primary name EXD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NVH0
EntryNameEXD2_HUMAN
FullNameExonuclease 3'-5' domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length621
SequenceStatuscomplete
DateCreated2003-10-24
DateModified2021-06-02

Ontological Relatives

GenesEXD2

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000287 magnesium ion binding
GO:0000724 double-strand break repair via homologous recombination
GO:0000729 DNA double-strand break processing
GO:0003676 nucleic acid binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005759 mitochondrial matrix
GO:0006302 double-strand break repair
GO:0008296 3'-5'-exodeoxyribonuclease activity
GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0008852 exodeoxyribonuclease I activity
GO:0016021 integral component of membrane
GO:0030145 manganese ion binding
GO:0031297 replication fork processing
GO:0042803 protein homodimerization activity
GO:0045111 intermediate filament cytoskeleton
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0090734 site of DNA damage

Subcellular Location

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Subcellular Location
Chromosome
Mitochondrion matrix
Mitochondrion outer membrane
Nucleus

Domains

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DomainNameCategoryType
IPR002562 3'-5' exonuclease domainDomainDomain
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
EXD2_HUMANCTIP_HUMANBioGRID, DIP26807646 details