Entity Details

Primary name KCND2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZV8
EntryNameKCND2_HUMAN
FullNamePotassium voltage-gated channel subfamily D member 2
TaxID9606
Evidenceevidence at protein level
Length630
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesKCND2

GO terms

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GOName
GO:0001508 action potential
GO:0005249 voltage-gated potassium channel activity
GO:0005250 A-type (transient outward) potassium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007268 chemical synaptic transmission
GO:0008076 voltage-gated potassium channel complex
GO:0014069 postsynaptic density
GO:0016021 integral component of membrane
GO:0019228 neuronal action potential
GO:0019233 sensory perception of pain
GO:0031226 intrinsic component of plasma membrane
GO:0032809 neuronal cell body membrane
GO:0034765 regulation of ion transmembrane transport
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0044853 plasma membrane raft
GO:0045211 postsynaptic membrane
GO:0045475 locomotor rhythm
GO:0046872 metal ion binding
GO:0051260 protein homooligomerization
GO:0061337 cardiac conduction
GO:0071456 cellular response to hypoxia
GO:0071805 potassium ion transmembrane transport
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099060 integral component of postsynaptic specialization membrane
GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Perikaryon

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003975 Potassium channel, voltage dependent, Kv4FamilyFamily
IPR004055 Potassium channel, voltage dependent, Kv4.2FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR021645 Shal-type voltage-gated potassium channels, N-terminalDomainDomain
IPR024587 Potassium channel, voltage dependent, Kv4, C-terminalDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00280 DisopyramideDrugbanksmall molecule
DB00458 ImipramineDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule