Entity Details

Primary name SE1L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBV2
EntryNameSE1L1_HUMAN
FullNameProtein sel-1 homolog 1
TaxID9606
Evidenceevidence at protein level
Length794
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesSEL1L

GO terms

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GOName
GO:0000836 Hrd1p ubiquitin ligase complex
GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006641 triglyceride metabolic process
GO:0007219 Notch signaling pathway
GO:0009306 protein secretion
GO:0016021 integral component of membrane
GO:0016567 protein ubiquitination
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030970 retrograde protein transport, ER to cytosol
GO:0036503 ERAD pathway
GO:0036513 Derlin-1 retrotranslocation complex
GO:0044322 endoplasmic reticulum quality control compartment
GO:0050821 protein stabilization
GO:0055085 transmembrane transport
GO:1904380 endoplasmic reticulum mannose trimming

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000562 Fibronectin type II domainDomainDomain
IPR006597 Sel1-like repeatRepeatRepeat
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR036943 Fibronectin type II domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
SE1L1_HUMANRL6_HUMANBioGRID, IntAct21988832 details
SE1L1_HUMANHYOU1_HUMANBioGRID26344197 27030672 details
SE1L1_HUMANTNR1A_HUMANIntAct14743216 details
SE1L1_HUMANFXRD2_HUMANBioGRID, DIP, IntAct19706418 22119785 28514442 details
SE1L1_HUMANOS9_HUMANBioGRID, DIP, IntAct, UniProt18264092 18502753 18711132 19346256 21454652 22119785 23097496 23356641 23867461 24899641 26551274 28827405 29496332 details
SE1L1_HUMANAUP1_HUMANBioGRID, DIP, IntAct, UniProt18711132 21857022 22119785 28827405 details
SE1L1_HUMANERN1_HUMANBioGRID, DIP19135427 26551274 details
SE1L1_HUMANSYVN1_HUMANBioGRID, IntAct, MINT, UniProt16186509 18264092 18502753 18711132 21454652 21903092 22119785 23356641 23867461 24366871 24807418 26424800 26471130 28827405 29496332 31477895 32614325 details
SE1L1_HUMANERLEC_HUMANBioGRID, IntAct18264092 22119785 23356641 details
SE1L1_HUMANDERL2_HUMANBioGRID, IntAct16186509 22119785 23867461 24366871 details
SE1L1_HUMANDERL1_HUMANBioGRID16186509 23867461 details
SE1L1_HUMANEDEM1_HUMANBioGRID19524542 21632540 24910992 details
SE1L1_HUMANRPN1_HUMANBioGRID19706418 details
SE1L1_HUMANSARAF_HUMANBioGRID18502753 details
SE1L1_HUMANUBXN4_HUMANBioGRID18711132 details
SE1L1_HUMANBASI_HUMANBioGRID23097496 details
SE1L1_HUMANEGFR_HUMANBioGRID23956138 details
SE1L1_HUMANUBP19_HUMANBioGRID24356957 details
SE1L1_HUMANHEY2_HUMANBioGRID24366871 details
SE1L1_HUMANHEY1_HUMANBioGRID24366871 details
SE1L1_HUMANSHH_HUMANBioGRID24366871 details
SE1L1_HUMANITB1_HUMANBioGRID24324549 details
SE1L1_HUMANITA5_HUMANBioGRID24324549 details
SE1L1_HUMANITB4_HUMANBioGRID24324549 details
SE1L1_HUMANTM129_HUMANBioGRID24807418 details
SE1L1_HUMANAMFR_HUMANBioGRID26424800 details
SE1L1_HUMANEDEM2_HUMANBioGRID24910992 details
SE1L1_HUMANEDEM3_HUMANBioGRID24910992 28366632 details
SE1L1_HUMANBIP_HUMANBioGRID27030672 details
SE1L1_HUMANVLDLR_HUMANBioGRID29371607 details