Entity Details

Primary name STK39_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UEW8
EntryNameSTK39_HUMAN
FullNameSTE20/SPS1-related proline-alanine-rich protein kinase
TaxID9606
Evidenceevidence at protein level
Length545
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSTK39

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0010820 positive regulation of T cell chemotaxis
GO:0016301 kinase activity
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019898 extrinsic component of membrane
GO:0019901 protein kinase binding
GO:0032414 positive regulation of ion transmembrane transporter activity
GO:0035556 intracellular signal transduction
GO:0036438 maintenance of lens transparency
GO:0038146 chemokine (C-X-C motif) ligand 12 signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0043268 positive regulation of potassium ion transport
GO:0046777 protein autophosphorylation
GO:0050727 regulation of inflammatory response
GO:0050801 ion homeostasis
GO:0071476 cellular hypotonic response
GO:0090188 negative regulation of pancreatic juice secretion
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1905408 negative regulation of creatine transmembrane transporter activity
GO:1990869 cellular response to chemokine
GO:2000650 negative regulation of sodium ion transmembrane transporter activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR024678 Serine/threonine-protein kinase OSR1/WNK, CCT domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule