Entity Details

Primary name LIMA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UHB6
EntryNameLIMA1_HUMAN
FullNameLIM domain and actin-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length759
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesLIMA1

GO terms

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GOName
GO:0001725 stress fiber
GO:0001726 ruffle
GO:0003785 actin monomer binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0008203 cholesterol metabolic process
GO:0015629 actin cytoskeleton
GO:0016477 cell migration
GO:0030299 intestinal cholesterol absorption
GO:0030835 negative regulation of actin filament depolymerization
GO:0031526 brush border membrane
GO:0031529 ruffle organization
GO:0032154 cleavage furrow
GO:0042632 cholesterol homeostasis
GO:0045296 cadherin binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR001781 Zinc finger, LIM-typeDomainDomain
IPR028740 LIM domain and actin-binding protein 1FamilyFamily

Diseases

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Interactions

83 interactions

InteractorPartnerSourcesPublicationsLink
LIMA1_HUMANSVIL_HUMANBioGRID, HPRD, IntAct20309963 26496610 details
LIMA1_HUMANDAPK1_HUMANBioGRID, IntAct29513927 details
LIMA1_HUMANMFHA1_HUMANBioGRID, IntAct29513927 details
LIMA1_HUMANA4_HUMANBioGRID21832049 details
LIMA1_HUMANUBC_HUMANBioGRID23314748 details
LIMA1_HUMAN1433T_HUMANBioGRID15161933 details
LIMA1_HUMANPTEN_HUMANBioGRID26561776 details
LIMA1_HUMANNEMO_HUMANIntAct14743216 details
LIMA1_HUMANM3K3_HUMANIntAct14743216 details
LIMA1_HUMANRIPK3_HUMANIntAct14743216 details
LIMA1_HUMAN1433Z_HUMANMINT15161933 details
LIMA1_HUMANDEN1A_HUMANBioGRID, IntAct26496610 27173435 unassigned1312 details
LIMA1_HUMANDCLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSI1L1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANKIF1C_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANGGYF1_HUMANIntActunassigned1312 details
LIMA1_HUMANNADK_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANAFAD_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANHDAC4_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMELK_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANGGYF2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSYDE1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANRPTOR_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANNAV1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANF110B_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANHDAC7_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSRS12_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMAGI1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANTESK2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANF110A_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSH3B4_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSRGP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMAST3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANIF4E2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANPKHA7_HUMANBioGRID, IntAct27173435 28877994 unassigned1312 details
LIMA1_HUMANAN34A_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANDEN4C_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSPD2A_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANM3K21_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANTBC25_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANPTN14_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANZN638_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANTIAM1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANCAMP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANCDK16_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMPIP3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMPIP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANNF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSIN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANRAB3I_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANEDC3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANDEP1B_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSH3R3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANKSR1_HUMANBioGRID, IntAct27086506 27173435 unassigned1312 details
LIMA1_HUMANPHLB2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANMYCPP_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANLARP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANLPIN3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANSTA13_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANGAB2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANAGAP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANPPM1H_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANUBP21_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANFA53C_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANINP5E_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANPKHA5_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANOSBL6_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANRTKN_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANNGAP_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LIMA1_HUMANCADH1_HUMANBioGRID, DIP18093941 25468996 details
LIMA1_HUMANCTNA1_HUMANDIP18093941 details
LIMA1_HUMANUBXN6_HUMANBioGRID22337587 details
LIMA1_HUMAN1433E_HUMANBioGRID17979178 details
LIMA1_HUMANBIRC3_HUMANBioGRID25569716 details
LIMA1_HUMANRN168_HUMANBioGRID27558965 details
LIMA1_HUMANSOX2_HUMANBioGRID21280222 details
LIMA1_HUMAN1433G_HUMANHPRD15324660 details