Entity Details

Primary name MCM8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJA3
EntryNameMCM8_HUMAN
FullNameDNA helicase MCM8
TaxID9606
Evidenceevidence at protein level
Length840
SequenceStatuscomplete
DateCreated2003-01-17
DateModified2021-06-02

Ontological Relatives

GenesMCM8

GO terms

Show/Hide Table
GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0007292 female gamete generation
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
GO:0032406 MutLbeta complex binding
GO:0032407 MutSalpha complex binding
GO:0032408 MutSbeta complex binding
GO:0036298 recombinational interstrand cross-link repair
GO:0036388 pre-replicative complex assembly
GO:0042555 MCM complex
GO:0048232 male gamete generation
GO:0050821 protein stabilization
GO:0071168 protein localization to chromatin
GO:0097362 MCM8-MCM9 complex

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001208 MCM domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031327 Mini-chromosome maintenance proteinFamilyFamily
IPR033762 MCM OB domainDomainDomain
IPR041562 MCM, AAA-lid domainDomainDomain

Diseases

Show/Hide Table