Entity Details

Primary name HSPB8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJY1
EntryNameHSPB8_HUMAN
FullNameHeat shock protein beta-8
TaxID9606
Evidenceevidence at protein level
Length196
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesHSPB8

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0016604 nuclear body
GO:0034620 cellular response to unfolded protein
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0101031 chaperone complex
GO:1900034 regulation of cellular response to heat
GO:1905337 positive regulation of aggrephagy

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001436 Alpha crystallin/Small heat shock protein, animal typeFamilyFamily
IPR002068 Alpha crystallin/Hsp20 domainDomainDomain
IPR008978 HSP20-like chaperoneFamilyHomologous superfamily
IPR042790 Heat shock protein beta-8, alpha-crystallin domain (ACD)DomainDomain
IPR043254 Heat shock protein beta-8FamilyFamily

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
HSPB8_HUMANHSPB7_HUMANBioGRID, IntAct14594798 16189514 25416956 32296183 details
HSPB8_HUMANBAG3_HUMANBioGRID, HPRD, IntAct, MINT11591653 16189514 21516116 25036637 26496610 28514442 29405094 30559338 32296183 details
HSPB8_HUMANCRYAB_HUMANBioGRID, IntAct16225851 details
HSPB8_HUMANHSPB3_HUMANBioGRID, IntAct16225851 details
HSPB8_HUMANHSPB6_HUMANBioGRID, HPRD, IntAct16225851 details
HSPB8_HUMANHSPB8_HUMANBioGRID, HPRD, IntAct14594798 details
HSPB8_HUMANHSPB2_HUMANBioGRID, IntAct11342557 14594798 details
HSPB8_HUMANHSPB1_HUMANBioGRID, HPRD, IntAct11342557 14594798 15122253 30669930 details
HSPB8_HUMANMLF2_HUMANBioGRID, IntAct23414517 25036637 details
HSPB8_HUMANQRIC1_HUMANBioGRID, IntAct25416956 32296183 details
HSPB8_HUMANDUS12_HUMANBioGRID, IntAct25416956 details
HSPB8_HUMANSOCS7_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANF214B_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANTPC6A_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANC2CD6_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANMOT6_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANMISP_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANRPIA_HUMANBioGRID, IntAct32296183 details
HSPB8_HUMANSYUA_HUMANBioGRID21905118 details
HSPB8_HUMANAT7L2_HUMANBioGRID32296183 details
HSPB8_HUMANE2AK1_HUMANDIP31273097 details
HSPB8_HUMANNOD1_HUMANDIP31273097 details
HSPB8_HUMANNOD2_HUMANDIP31273097 details
HSPB8_HUMANDNJB6_HUMANBioGRID22366786 details
HSPB8_HUMANKPCA_HUMANHPRD11342557 details
HSPB8_HUMANMK03_HUMANHPRD11342557 details
HSPB8_HUMANCSK21_HUMANHPRD11342557 details