Entity Details

Primary name SYYM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2Z4
EntryNameSYYM_HUMAN
FullNameTyrosine--tRNA ligase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length477
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesYARS2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0016604 nuclear body
GO:0042803 protein homodimerization activity
GO:0043039 tRNA aminoacylation
GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation
GO:0072545 tyrosine binding

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001412 Aminoacyl-tRNA synthetase, class I, conserved siteSiteConserved site
IPR002305 Aminoacyl-tRNA synthetase, class IcFamilyFamily
IPR002307 Tyrosine-tRNA ligaseFamilyFamily
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR024088 Tyrosine-tRNA ligase, bacterial-typeFamilyFamily
IPR036986 RNA-binding S4 domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00135 TyrosineDrugbanksmall molecule

Interactions

5 interactions