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Entity Details
Primary name
PKHM1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9Y4G2
EntryName
PKHM1_HUMAN
FullName
Pleckstrin homology domain-containing family M member 1
TaxID
9606
Evidence
evidence at protein level
Length
1056
SequenceStatus
complete
DateCreated
2007-11-13
DateModified
2021-06-02
Ontological Relatives
Genes
PLEKHM1
GO terms
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GO
Name
GO:0005730
nucleolus
GO:0005764
lysosome
GO:0005765
lysosomal membrane
GO:0010008
endosome membrane
GO:0015031
protein transport
GO:0032418
lysosome localization
GO:0035556
intracellular signal transduction
GO:0043231
intracellular membrane-bounded organelle
GO:0044754
autolysosome
GO:0045780
positive regulation of bone resorption
GO:0046872
metal ion binding
GO:0061909
autophagosome-lysosome fusion
GO:1900029
positive regulation of ruffle assembly
GO:1902774
late endosome to lysosome transport
Subcellular Location
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Subcellular Location
Autolysosome membrane
Endosome membrane
Late endosome membrane
Lysosome membrane
Domains
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Domain
Name
Category
Type
IPR001849
Pleckstrin homology domain
Domain
Domain
IPR002219
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain
Domain
IPR004012
RUN domain
Domain
Domain
IPR011993
PH-like domain superfamily
Family
Homologous superfamily
IPR025258
Putative zinc-RING and/or ribbon
Domain
Domain
IPR037213
RUN domain superfamily
Family
Homologous superfamily
IPR042827
PLEKHM1, PH domain
Domain
Domain
Diseases
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Drugs
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Interactions
18 interactions
Interactor
Partner
Sources
Publications
Link
PKHM1_HUMAN
GA45G_HUMAN
BioGRID, IntAct
15383276
details
PKHM1_HUMAN
PA1B3_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PKHM1_HUMAN
SPB9_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PKHM1_HUMAN
IF2B_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PKHM1_HUMAN
PHOCN_HUMAN
BioGRID, HPRD, IntAct
16169070
details
PKHM1_HUMAN
BID_HUMAN
BioGRID, MINT
21900206
details
PKHM1_HUMAN
MK06_HUMAN
BioGRID, MINT
21900206
details
PKHM1_HUMAN
TRI54_HUMAN
BioGRID, IntAct
31391242
details
PKHM1_HUMAN
NSMA2_HUMAN
IntAct
16169070
details
PKHM1_HUMAN
RAB7A_HUMAN
BioGRID, IntAct
27291868
27777970
details
PKHM1_HUMAN
CTDS1_HUMAN
MINT
21653829
details
PKHM1_HUMAN
DEFI8_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
KIFC1_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
TPX2_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
FA98A_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
NDEL1_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
M3K7_HUMAN
BioGRID
27777970
details
PKHM1_HUMAN
RAP1B_HUMAN
BioGRID
27777970
details
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