Entity Details

Primary name TRPV2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5S1
EntryNameTRPV2_HUMAN
FullNameTransient receptor potential cation channel subfamily V member 2
TaxID9606
Evidenceevidence at protein level
Length764
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesTRPV2

GO terms

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GOName
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007600 sensory perception
GO:0009266 response to temperature stimulus
GO:0009408 response to heat
GO:0009986 cell surface
GO:0015075 ion transmembrane transporter activity
GO:0032584 growth cone membrane
GO:0042470 melanosome
GO:0044295 axonal growth cone
GO:0044297 cell body
GO:0045773 positive regulation of axon extension
GO:0070588 calcium ion transmembrane transport
GO:0090280 positive regulation of calcium ion import
GO:0098703 calcium ion import across plasma membrane
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Melanosome

Domains

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DomainNameCategoryType
IPR002110 Ankyrin repeatRepeatRepeat
IPR005821 Ion transport domainDomainDomain
IPR008347 Transient receptor potential channel, vanilloid 1-4FamilyFamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR024862 Transient receptor potential cation channel subfamily VFamilyFamily
IPR024865 Transient receptor potential channel, vanilloid 2FamilyFamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09061 CannabidiolDrugbanksmall molecule
DB11755 TetrahydrocannabivarinDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule
DB14050 CannabidivarinDrugbanksmall molecule