Entity Details

Primary name AUP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y679
EntryNameAUP1_HUMAN
FullNameLipid droplet-regulating VLDL assembly factor AUP1
TaxID9606
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesAUP1

GO terms

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GOName
GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex
GO:0005776 autophagosome
GO:0005783 endoplasmic reticulum
GO:0005811 lipid droplet
GO:0009615 response to virus
GO:0016020 membrane
GO:0016032 viral process
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031410 cytoplasmic vesicle
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031625 ubiquitin protein ligase binding
GO:0034389 lipid droplet organization
GO:0043130 ubiquitin binding
GO:0061724 lipophagy
GO:0070062 extracellular exosome
GO:0071712 ER-associated misfolded protein catabolic process
GO:0097027 ubiquitin-protein transferase activator activity
GO:0140042 lipid droplet formation
GO:1990044 protein localization to lipid droplet

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Endoplasmic reticulum membrane
Lipid droplet

Domains

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DomainNameCategoryType
IPR003892 Ubiquitin system component CUEDomainDomain

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
AUP1_HUMANRNF11_HUMANBioGRID, MINT15231748 details
AUP1_HUMANUB2G2_HUMANBioGRID, IntAct17353931 21127063 21857022 22119785 23223569 32296183 details
AUP1_HUMANUB2E3_HUMANIntAct19549727 details
AUP1_HUMANOPRM_HUMANBioGRID, IntAct23840749 details
AUP1_HUMANGPR35_HUMANBioGRID, MINT28298427 details
AUP1_HUMANITA2B_HUMANBioGRID12042322 details
AUP1_HUMANITA1_HUMANBioGRID12042322 details
AUP1_HUMANITA2_HUMANBioGRID12042322 details
AUP1_HUMANITAV_HUMANBioGRID12042322 details
AUP1_HUMANITAM_HUMANBioGRID12042322 details
AUP1_HUMANITA5_HUMANBioGRID12042322 details
AUP1_HUMANUBC_HUMANBioGRID21857022 31699778 details
AUP1_HUMANMDC1_HUMANBioGRID22990118 details
AUP1_HUMANMAGA6_HUMANIntAct17353931 details
AUP1_HUMANBRF2_HUMANIntAct17353931 details
AUP1_HUMANOPRK_HUMANBioGRID, IntAct23840749 details
AUP1_HUMANAPOB_HUMANBioGRID, IntAct26186194 28183703 28514442 details
AUP1_HUMANSE1L1_HUMANBioGRID, DIP, IntAct, UniProt18711132 21857022 22119785 28827405 details
AUP1_HUMANSYVN1_HUMANBioGRID, IntAct, UniProt21857022 22119785 28827405 31056421 details
AUP1_HUMANTERA_HUMANBioGRID21857022 29540532 details
AUP1_HUMANOS9_HUMANBioGRID21857022 details
AUP1_HUMANFAF2_HUMANBioGRID21857022 26389662 details
AUP1_HUMANSTT3B_HUMANBioGRID21857022 details
AUP1_HUMANUB2J1_HUMANBioGRID20435896 21857022 details
AUP1_HUMANKCND3_HUMANBioGRID17725712 details
AUP1_HUMANAMFR_HUMANBioGRID23223569 32614325 details
AUP1_HUMANHMDH_HUMANBioGRID23223569 details
AUP1_HUMANRN139_HUMANBioGRID23223569 details
AUP1_HUMANOPRD_HUMANBioGRID23840749 details
AUP1_HUMANST7_HUMANBioGRID29395067 details
AUP1_HUMANRNF26_HUMANBioGRID32614325 details