Entity Details

Primary name MD1L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6D9
EntryNameMD1L1_HUMAN
FullNameMitotic spindle assembly checkpoint protein MAD1
TaxID9606
Evidenceevidence at protein level
Length718
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesMAD1L1

GO terms

Show/Hide Table
GOName
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005819 spindle
GO:0005829 cytosol
GO:0007052 mitotic spindle organization
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0042130 negative regulation of T cell proliferation
GO:0042802 identical protein binding
GO:0043515 kinetochore binding
GO:0044615 nuclear pore nuclear basket
GO:0048538 thymus development
GO:0051301 cell division
GO:0051315 attachment of mitotic spindle microtubules to kinetochore
GO:0072686 mitotic spindle
GO:0090235 regulation of metaphase plate congression

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Cytoplasm
Nucleus
Nucleus envelope

Domains

Show/Hide Table
DomainNameCategoryType
IPR008672 Spindle assembly checkpoint component Mad1FamilyFamily

Diseases

Show/Hide Table

Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
MD1L1_HUMANTEX11_HUMANBioGRID, HPRD, IntAct16189514 27107012 details
MD1L1_HUMANNINL_HUMANBioGRID, HPRD, IntAct16189514 details
MD1L1_HUMANNONO_HUMANBioGRID, HPRD, IntAct16189514 details
MD1L1_HUMANF131C_HUMANBioGRID, HPRD, IntAct16189514 details
MD1L1_HUMANTRI29_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
MD1L1_HUMANAMOL2_HUMANBioGRID, HPRD, IntAct16189514 details
MD1L1_HUMANMD1L1_HUMANBioGRID, DIP, HPRD, IntAct12006501 16189514 22493223 27107012 9546394 details
MD1L1_HUMANMD2L1_HUMANBioGRID, DIP, HPRD, IntAct, MINT10660610 11459826 11707408 15694304 16189514 18318601 18692475 21041666 21525009 21772247 21988832 22493223 24581499 25012665 25422469 26258632 26264872 26496610 26986935 29997244 31467278 31515488 31588029 32296183 32814053 details
MD1L1_HUMANCOIL_HUMANBioGRID, HPRD, IntAct16713569 details
MD1L1_HUMANTPM3_HUMANBioGRID, IntAct, MINT21516116 25416956 25910212 32296183 details
MD1L1_HUMANBAG5_HUMANBioGRID, IntAct22863883 25036637 25416956 26186194 28514442 32296183 details
MD1L1_HUMANTPR_HUMANBioGRID, IntAct24581499 31588029 details
MD1L1_HUMANTSH3_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANC19L2_HUMANBioGRID, IntAct25416956 32296183 details
MD1L1_HUMANZSC32_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANNEBL_HUMANBioGRID, IntAct25416956 31515488 32296183 details
MD1L1_HUMANRNF8_HUMANBioGRID, IntAct25416956 31515488 32296183 details
MD1L1_HUMANTPM1_HUMANBioGRID, IntAct25416956 25910212 26186194 26871637 28514442 32296183 details
MD1L1_HUMANLOX5_HUMANBioGRID, IntAct25416956 25910212 32296183 details
MD1L1_HUMANPSA1_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANMFAP1_HUMANBioGRID, IntAct25416956 32296183 details
MD1L1_HUMANLEGL_HUMANBioGRID, IntAct25416956 32296183 details
MD1L1_HUMANCCHCR_HUMANBioGRID, IntAct25416956 29892012 32296183 details
MD1L1_HUMANHAUS1_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANT22D3_HUMANBioGRID, IntAct25416956 32296183 details
MD1L1_HUMANYJU2_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANSPAT2_HUMANBioGRID, IntAct25416956 details
MD1L1_HUMANUBP15_HUMANBioGRID, IntAct25416956 32296183 details
MD1L1_HUMANSPT5H_HUMANBioGRID, IntAct27107012 details
MD1L1_HUMANVIME_HUMANIntAct27107012 details
MD1L1_HUMANTRI27_HUMANIntAct27107012 details
MD1L1_HUMANPLK4_HUMANIntAct27107012 details
MD1L1_HUMANLENG1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANMIEAP_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANTEX33_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANSYT6_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANCDK18_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANKIF9_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANNTAQ1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANRBTN1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANF90A1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANTCAF1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANATG5_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANLMO3_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANSYT17_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANCAN7_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANCDC37_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANPPR18_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANDRC4_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANLNX1_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANTSG10_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANGPKOW_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANCCD57_HUMANBioGRID, IntAct32296183 details
MD1L1_HUMANCENPE_HUMANDIP26258632 details
MD1L1_HUMANGCP4_HUMANBioGRID, HPRD16189514 details
MD1L1_HUMANUBC_HUMANBioGRID23314748 details
MD1L1_HUMANSIN3A_HUMANBioGRID, HPRD11106735 22783022 details
MD1L1_HUMANBIRC2_HUMANBioGRID30181285 details
MD1L1_HUMANLMO7_HUMANBioGRID29158164 details
MD1L1_HUMANPML_HUMANBioGRID30948704 details
MD1L1_HUMANPIBF1_HUMANBioGRID32296183 details
MD1L1_HUMANMLX_HUMANHPRD10593926 details
MD1L1_HUMANNDC80_HUMANHPRD12351790 details
MD1L1_HUMANSIN3B_HUMANHPRD11101889 11370785 details
MD1L1_HUMANNEK2_HUMANHPRD14978040 details
MD1L1_HUMANZW10_HUMANBioGRID, UniProt15824131 details
MD1L1_HUMANMD2BP_HUMANBioGRID, MINT21772247 22100920 details
MD1L1_HUMANFXR1_HUMANMINT21653829 details
MD1L1_HUMANHDAC1_HUMANBioGRID, HPRD15388328 details
MD1L1_HUMANHDAC2_HUMANBioGRID, HPRD15388328 details
MD1L1_HUMANMNT_HUMANBioGRID18271930 details
MD1L1_HUMANNRDC_HUMANBioGRID22294699 details
MD1L1_HUMANCDC27_HUMANBioGRID22100920 details
MD1L1_HUMANMT21C_HUMANBioGRID23349634 details
MD1L1_HUMANPCH2_HUMANBioGRID25012665 details
MD1L1_HUMANSUMO1_HUMANBioGRID30948704 details
MD1L1_HUMANSUMO2_HUMANBioGRID30948704 details
MD1L1_HUMANUBF1_HUMANHPRD15282543 details
MD1L1_HUMANSVIL_HUMANHPRD16880273 details
MD1L1_HUMANMAX_HUMANHPRD10229200 details