Entity Details

Primary name NCOA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6Q9
EntryNameNCOA3_HUMAN
FullNameNuclear receptor coactivator 3
TaxID9606
Evidenceevidence at protein level
Length1424
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesNCOA3

GO terms

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GOName
GO:0000785 chromatin
GO:0000993 RNA polymerase II complex binding
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016922 nuclear receptor binding
GO:0030374 nuclear receptor coactivator activity
GO:0032870 cellular response to hormone stimulus
GO:0032991 protein-containing complex
GO:0035624 receptor transactivation
GO:0043697 cell dedifferentiation
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046966 thyroid hormone receptor binding
GO:0046983 protein dimerization activity
GO:0047485 protein N-terminus binding
GO:0070062 extracellular exosome
GO:0071392 cellular response to estradiol stimulus
GO:0097718 disordered domain specific binding
GO:1902459 positive regulation of stem cell population maintenance
GO:2000035 regulation of stem cell division

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR009110 Nuclear receptor coactivator, interlockingFamilyHomologous superfamily
IPR010011 Nuclear receptor coactivator, DUF1518DomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013767 PAS foldDomainDomain
IPR014920 Nuclear receptor coactivator, Ncoa-type, interlockingDomainDomain
IPR014935 Nuclear receptor coactivator, receptor-binding domainDomainDomain
IPR017426 Nuclear receptor coactivatorFamilyFamily
IPR028818 Nuclear receptor coactivator 3FamilyFamily
IPR032565 Domain of unknown function DUF4927DomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037077 Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

116 interactions

InteractorPartnerSourcesPublicationsLink
NCOA3_HUMANNEMO_HUMANBioGRID, HPRD, UniProt11971985 16051665 details
NCOA3_HUMANIKKB_HUMANBioGRID, HPRD, UniProt11971985 15383283 16051665 16135815 details
NCOA3_HUMANIKKA_HUMANBioGRID, HPRD, UniProt11971985 15383283 15808510 16051665 details
NCOA3_HUMANCBP_HUMANBioGRID, HPRD, IntAct, UniProt11076796 11823864 11971985 15383283 16227615 17043108 21632823 21914189 26267537 8616895 9192892 9267036 9346901 9445475 details
NCOA3_HUMANPSME3_HUMANBioGRID, HPRD, IntAct16051665 16439211 details
NCOA3_HUMANRARA_HUMANBioGRID, HPRD, IntAct, MINT12665583 15604093 16456540 17475621 19144644 20413580 25303530 9192892 9346901 details
NCOA3_HUMANMK14_HUMANBioGRID, HPRD, MINT15383283 16135815 16456540 details
NCOA3_HUMANPSB9_HUMANBioGRID, HPRD, MINT16957778 details
NCOA3_HUMANESR1_HUMANBioGRID, HPRD, IntAct10490106 11050174 11353774 11376110 11389589 12554772 12630920 12714702 14766010 14966289 15145444 15383283 16331275 16923966 17158759 17646391 18484708 18645020 19491275 20181721 20392877 21182203 23403292 25728767 26153859 26166704 26487511 28844863 30418174 9192892 9346901 9765300 details
NCOA3_HUMANNCOA1_HUMANBioGRID, MINT17476305 18267973 details
NCOA3_HUMANEP300_HUMANBioGRID, HPRD, IntAct10490106 10655477 10866661 11823864 15145939 16227615 16923966 20368990 23065768 25728767 9267036 details
NCOA3_HUMANESR2_HUMANBioGRID, HPRD, IntAct10681591 11376110 11389589 11500849 12554772 17158759 21182203 9765300 details
NCOA3_HUMANTHB_HUMANBioGRID, HPRD, I2D15604093 20956942 9346901 details
NCOA3_HUMANSPOP_HUMANBioGRID, I2D21577200 23559371 28805822 29996942 details
NCOA3_HUMANKC1E_HUMANBioGRID, I2D21577200 details
NCOA3_HUMANANDR_HUMANBioGRID, HPRD, UniProt10965917 11747336 14966121 15563469 16951154 21047772 32668201 details
NCOA3_HUMANCARM1_HUMANBioGRID, DIP, IntAct15383283 16923966 16938873 17043108 18511550 26267537 details
NCOA3_HUMANE2F1_HUMANBioGRID, DIP, HPRD15169882 16648476 16938873 details
NCOA3_HUMANOPTN_HUMANIntAct32814053 details
NCOA3_HUMANBRCA1_HUMANBioGRID14578343 16860316 details
NCOA3_HUMANANR11_HUMANBioGRID15184363 details
NCOA3_HUMANNPAS2_HUMANBioGRID, HPRD14645221 details
NCOA3_HUMANGCR_HUMANBioGRID11266503 12917342 18160712 28611094 31182584 details
NCOA3_HUMAN1433T_HUMANBioGRID11266503 details
NCOA3_HUMANANM1_HUMANBioGRID, HPRD11050077 details
NCOA3_HUMANNR4A1_HUMANBioGRID, HPRD12082103 details
NCOA3_HUMANCOT1_HUMANBioGRID10652338 details
NCOA3_HUMANRXRA_HUMANBioGRID, HPRD11027271 11851396 15863722 9267036 9346901 details
NCOA3_HUMANERR1_HUMANBioGRID, HPRD10598588 15604093 details
NCOA3_HUMANERR2_HUMANBioGRID, HPRD10598588 details
NCOA3_HUMANNKX21_HUMANBioGRID11076796 15449938 details
NCOA3_HUMANNR0B2_HUMANBioGRID11668176 details
NCOA3_HUMANNR5A2_HUMANBioGRID11668176 details
NCOA3_HUMANVDR_HUMANBioGRID10224118 10681591 12893883 15888456 15919092 20733005 details
NCOA3_HUMANPRGR_HUMANBioGRID, HPRD10757795 15937332 16728408 19357364 details
NCOA3_HUMANH31T_HUMANBioGRID11163245 14747462 details
NCOA3_HUMANH4_HUMANBioGRID11163245 14747462 details
NCOA3_HUMANABL1_HUMANBioGRID18765637 details
NCOA3_HUMANFOS_HUMANBioGRID18511550 details
NCOA3_HUMANNCOR1_HUMANBioGRID12089344 details
NCOA3_HUMANPPARG_HUMANBioGRID, HPRD11027271 11500849 11877444 15604093 15888456 19596656 23178929 details
NCOA3_HUMANKAT2B_HUMANBioGRID, HPRD9267036 9346901 9445475 details
NCOA3_HUMANNCOR2_HUMANBioGRID, HPRD20392877 9267036 details
NCOA3_HUMANCDKN3_HUMANBioGRID21577200 details
NCOA3_HUMANIQCK_HUMANBioGRID21577200 details
NCOA3_HUMANBABA2_HUMANBioGRID21577200 details
NCOA3_HUMANDCTN6_HUMANBioGRID21577200 details
NCOA3_HUMANRARG_HUMANBioGRID, HPRD12665583 15604093 16456540 details
NCOA3_HUMANNR1H3_HUMANBioGRID, HPRD15604093 details
NCOA3_HUMANNR1H2_HUMANBioGRID, HPRD15604093 details
NCOA3_HUMANMK01_HUMANBioGRID, HPRD10866661 15383283 16456540 details
NCOA3_HUMANMK08_HUMANBioGRID15383283 details
NCOA3_HUMANGSK3B_HUMANBioGRID15383283 details
NCOA3_HUMANTP53B_HUMANBioGRID21914189 details
NCOA3_HUMANKPCZ_HUMANBioGRID18313384 details
NCOA3_HUMANMYCD_HUMANBioGRID17360478 details
NCOA3_HUMANPIN1_HUMANBioGRID, HPRD16227615 details
NCOA3_HUMANP53_HUMANBioGRID10551785 details
NCOA3_HUMANNR1I2_HUMANBioGRID, HPRD16219912 details
NCOA3_HUMANMMS19_HUMANBioGRID, HPRD11279242 details
NCOA3_HUMANARNT2_HUMANBioGRID24722188 details
NCOA3_HUMANETV1_HUMANBioGRID14747462 details
NCOA3_HUMANPPARD_HUMANBioGRID15001550 15888456 details
NCOA3_HUMANPPARA_HUMANBioGRID15888456 details
NCOA3_HUMANNR1I3_HUMANBioGRID15888456 details
NCOA3_HUMANMN1_HUMANBioGRID12569362 details
NCOA3_HUMANMRTFA_HUMANBioGRID17360478 details
NCOA3_HUMANMRTFB_HUMANBioGRID17360478 details
NCOA3_HUMANHNF1A_HUMANBioGRID10777539 details
NCOA3_HUMANS22A2_HUMANBioGRID31318583 details
NCOA3_HUMANSUFU_HUMANHPRD14611647 details
NCOA3_HUMANDDX5_HUMANHPRD11250900 details
NCOA3_HUMANTF65_HUMANBioGRID, HPRD, MINT16331275 16456540 details
NCOA3_HUMANPTEN_HUMANBioGRID, Molecular Connections23514585 details
NCOA3_HUMANRAB28_HUMANBioGRID, IntAct27173435 unassigned1312 details
NCOA3_HUMANATAD2_HUMANBioGRID, DIP, HPRD17998543 details
NCOA3_HUMANCCND1_HUMANBioGRID, HPRD9832502 details
NCOA3_HUMANNCOA2_HUMANBioGRID11971985 18267973 details
NCOA3_HUMANRO52_HUMANBioGRID11971985 16051665 details
NCOA3_HUMANETS1_HUMANBioGRID15788656 details
NCOA3_HUMANETS2_HUMANBioGRID15788656 details
NCOA3_HUMANTHA_HUMANBioGRID11117530 details
NCOA3_HUMANSTAT6_HUMANBioGRID15145939 details
NCOA3_HUMANSMAD2_HUMANBioGRID16751102 18003620 details
NCOA3_HUMANSMAD3_HUMANBioGRID18003620 details
NCOA3_HUMANSPTA1_HUMANBioGRID16051665 details
NCOA3_HUMANMYH9_HUMANBioGRID16051665 details
NCOA3_HUMANACTS_HUMANBioGRID16051665 details
NCOA3_HUMANANXA2_HUMANBioGRID16051665 details
NCOA3_HUMANTPR_HUMANBioGRID16051665 details
NCOA3_HUMANMORC2_HUMANBioGRID16051665 details
NCOA3_HUMANNFAC3_HUMANBioGRID16051665 details
NCOA3_HUMANCUL3_HUMANBioGRID22147914 details
NCOA3_HUMANNFKB1_HUMANBioGRID15383283 details
NCOA3_HUMANRFX1_HUMANBioGRID20181721 details
NCOA3_HUMANPRS8_HUMANBioGRID19144644 details
NCOA3_HUMANPSA3_HUMANBioGRID18313384 details
NCOA3_HUMANUBE3A_HUMANBioGRID16951183 details
NCOA3_HUMANFBXW7_HUMANBioGRID23514585 details
NCOA3_HUMANPIAS1_HUMANBioGRID22283414 details
NCOA3_HUMANFOXG1_HUMANBioGRID23660594 details
NCOA3_HUMANCTSL2_HUMANBioGRID26674342 details
NCOA3_HUMANPHF1_HUMANBioGRID29846670 details
NCOA3_HUMANFLII_HUMANBioGRID14966289 details
NCOA3_HUMANSMG7_HUMANBioGRID29395067 details
NCOA3_HUMANJUN_HUMANHPRD11477071 details
NCOA3_HUMANRXRB_HUMANHPRD9267036 details
NCOA3_HUMANTBP_HUMANHPRD9267036 details
NCOA3_HUMANBMP6_HUMANHPRD10504300 details
NCOA3_HUMANBMP7_HUMANHPRD7791754 details
NCOA3_HUMAN1433F_HUMANHPRD11266503 details
NCOA3_HUMANNCOA3_HUMANHPRD10598588 9812974 details
NCOA3_HUMANSMCE1_HUMANHPRD12145209 details
NCOA3_HUMANTF2B_HUMANHPRD9267036 details
NCOA3_HUMANSUMO1_HUMANHPRD16760465 details
NCOA3_HUMANRARB_HUMANHPRD12665583 details