Entity Details

Primary name NRP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60462
EntryNameNRP2_HUMAN
FullNameNeuropilin-2
TaxID9606
Evidenceevidence at protein level
Length931
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNRP2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002116 semaphorin receptor complex
GO:0003148 outflow tract septum morphogenesis
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0008201 heparin binding
GO:0010595 positive regulation of endothelial cell migration
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0017154 semaphorin receptor activity
GO:0019838 growth factor binding
GO:0019955 cytokine binding
GO:0021612 facial nerve structural organization
GO:0021649 vestibulocochlear nerve structural organization
GO:0021675 nerve development
GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030424 axon
GO:0036486 ventral trunk neural crest cell migration
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048846 axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0061549 sympathetic ganglion development
GO:0061551 trigeminal ganglion development
GO:0097374 sensory neuron axon guidance
GO:0097490 sympathetic neuron projection extension
GO:0097491 sympathetic neuron projection guidance
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099175 regulation of postsynapse organization
GO:1901166 neural crest cell migration involved in autonomic nervous system development
GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1903375 facioacoustic ganglion development
GO:1904835 dorsal root ganglion morphogenesis
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Membrane
Secreted

Domains

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DomainNameCategoryType
IPR000421 Coagulation factor 5/8 C-terminal domainDomainDomain
IPR000859 CUB domainDomainDomain
IPR000998 MAM domainDomainDomain
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR014648 NeuropilinFamilyFamily
IPR022579 Neuropilin, C-terminalDomainDomain
IPR027143 Neuropilin-2FamilyFamily
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily

Diseases

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