Entity Details

Primary name MOT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60669
EntryNameMOT2_HUMAN
FullNameMonocarboxylate transporter 2
TaxID9606
Evidenceevidence at protein level
Length478
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSLC16A7

GO terms

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GOName
GO:0005477 pyruvate secondary active transmembrane transporter activity
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008028 monocarboxylic acid transmembrane transporter activity
GO:0015129 lactate transmembrane transporter activity
GO:0015293 symporter activity
GO:0015718 monocarboxylic acid transport
GO:0016021 integral component of membrane
GO:0035873 lactate transmembrane transport
GO:0050833 pyruvate transmembrane transporter activity
GO:0150104 transport across blood-brain barrier
GO:1901475 pyruvate transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR004743 Monocarboxylate transporterFamilyFamily
IPR011701 Major facilitator superfamilyFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR027178 Monocarboxylate transporter 2FamilyFamily
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00119 Pyruvic acidDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB01440 gamma-Hydroxybutyric acidDrugbanksmall molecule
DB01762 Acetoacetic acidDrugbanksmall molecule
DB03066 D-Lactic acidDrugbanksmall molecule
DB03773 alpha-D-quinovopyranoseDrugbanksmall molecule
DB04074 alpha-KetoisovalerateDrugbanksmall molecule
DB04216 QuercetinDrugbanksmall molecule
DB04398 Lactic acidDrugbanksmall molecule
DB04552 Niflumic acidDrugbanksmall molecule