Entity Details

Primary name ICMT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60725
EntryNameICMT_HUMAN
FullNameProtein-S-isoprenylcysteine O-methyltransferase
TaxID9606
Evidenceevidence at protein level
Length284
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesICMT

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0003880 protein C-terminal carboxyl O-methyltransferase activity
GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006464 cellular protein modification process
GO:0006481 C-terminal protein methylation
GO:0006612 protein targeting to membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043687 post-translational protein modification

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR007269 Isoprenylcysteine carboxyl methyltransferaseFamilyFamily
IPR025770 Protein-S-isoprenylcysteine O-methyltransferaseFamilyFamily

Diseases

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