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Entity Details
Primary name
DEPD5_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O75140
EntryName
DEPD5_HUMAN
FullName
GATOR complex protein DEPDC5
TaxID
9606
Evidence
evidence at protein level
Length
1603
SequenceStatus
complete
DateCreated
2002-04-03
DateModified
2021-06-02
Ontological Relatives
Genes
DEPDC5
GO terms
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GO
Name
GO:0005096
GTPase activator activity
GO:0005764
lysosome
GO:0005765
lysosomal membrane
GO:0005829
cytosol
GO:0010506
regulation of autophagy
GO:0032007
negative regulation of TOR signaling
GO:0034198
cellular response to amino acid starvation
GO:0035556
intracellular signal transduction
GO:0043547
positive regulation of GTPase activity
GO:0044877
protein-containing complex binding
GO:0048471
perinuclear region of cytoplasm
GO:1904262
negative regulation of TORC1 signaling
GO:1990130
GATOR1 complex
Subcellular Location
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Subcellular Location
Cytoplasm
Lysosome membrane
Domains
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Domain
Name
Category
Type
IPR000591
DEP domain
Domain
Domain
IPR027244
Vacuolar membrane-associated protein Iml1
Family
Family
IPR036388
Winged helix-like DNA-binding domain superfamily
Family
Homologous superfamily
IPR036390
Winged helix DNA-binding domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
Show/Hide Table
Interactions
23 interactions
Interactor
Partner
Sources
Publications
Link
DEPD5_HUMAN
DPPA3_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
UBP2_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
MD2L1_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
TCPG_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
SYT17_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
MTMR9_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
MD2L2_HUMAN
BioGRID, IntAct
32296183
details
DEPD5_HUMAN
RRAGC_HUMAN
BioGRID, DIP, IntAct
23723238
25366275
28199315
details
DEPD5_HUMAN
RRAGB_HUMAN
BioGRID, IntAct
23723238
28199315
details
DEPD5_HUMAN
MEOX2_HUMAN
BioGRID
32296183
details
DEPD5_HUMAN
NPRL2_HUMAN
BioGRID, DIP, IntAct
23723238
25263562
25366275
25936802
28199306
28199315
28514442
details
DEPD5_HUMAN
KPTN_HUMAN
BioGRID, IntAct
28199306
28514442
details
DEPD5_HUMAN
KICS2_HUMAN
BioGRID, IntAct
28199306
28514442
details
DEPD5_HUMAN
ITFG2_HUMAN
BioGRID, IntAct
28199306
28514442
details
DEPD5_HUMAN
SZT2_HUMAN
BioGRID, IntAct
28199306
28199315
28514442
details
DEPD5_HUMAN
NPRL3_HUMAN
BioGRID, DIP, IntAct
23723238
25263562
25366275
28199306
28199315
details
DEPD5_HUMAN
RRAGA_HUMAN
BioGRID, DIP
23723238
25366275
25936802
details
DEPD5_HUMAN
WDR24_HUMAN
BioGRID, IntAct
23723238
28199306
28199315
details
DEPD5_HUMAN
MIO_HUMAN
BioGRID, IntAct
28199306
28199315
details
DEPD5_HUMAN
CDC5L_HUMAN
IntAct
31413325
details
DEPD5_HUMAN
WDR59_HUMAN
BioGRID
28199306
details
DEPD5_HUMAN
LAMP1_HUMAN
BioGRID
28199306
details
DEPD5_HUMAN
RRAGD_HUMAN
BioGRID
26582740
details
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