Entity Details

Primary name MMP23_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75900
EntryNameMMP23_HUMAN
FullNameMatrix metalloproteinase-23
TaxID9606
Evidenceevidence at protein level
Length390
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesMMP23B

GO terms

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GOName
GO:0000003 reproduction
GO:0004222 metalloendopeptidase activity
GO:0005615 extracellular space
GO:0005789 endoplasmic reticulum membrane
GO:0006508 proteolysis
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016021 integral component of membrane
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Membrane

Domains

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DomainNameCategoryType
IPR001818 Peptidase M10, metallopeptidaseDomainDomain
IPR003582 ShKT domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR006026 Peptidase, metallopeptidaseDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR021190 Peptidase M10AFamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR028687 Matrix metalloproteinase-23FamilyFamily
IPR033739 Peptidase M10A, catalytic domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00786 MarimastatDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MMP23_HUMANGLRX1_HUMANBioGRID, IntAct21988832 details
MMP23_HUMANSRPK2_HUMANBioGRID26167880 details