Entity Details

Primary name ERG24_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO76062
EntryNameERG24_HUMAN
FullNameDelta(14)-sterol reductase TM7SF2
TaxID9606
Evidenceevidence at protein level
Length418
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesTM7SF2

GO terms

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GOName
GO:0005637 nuclear inner membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0006695 cholesterol biosynthetic process
GO:0016126 sterol biosynthetic process
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0019216 regulation of lipid metabolic process
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0050613 delta14-sterol reductase activity
GO:0050661 NADP binding

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001171 Ergosterol biosynthesis ERG4/ERG24FamilyFamily
IPR018083 Sterol reductase, conserved siteSiteConserved site

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ERG24_HUMANRAP2A_HUMANBioGRID, IntAct18624398 details
ERG24_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
ERG24_HUMANLCE2C_HUMANBioGRID, IntAct32296183 details
ERG24_HUMANACM4_HUMANBioGRID, MINT28298427 details