Entity Details

Primary name DDAH1_HUMAN
Entity type UniProt
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Details

AccessionO94760
EntryNameDDAH1_HUMAN
FullNameN(G),N(G)-dimethylarginine dimethylaminohydrolase 1
TaxID9606
Evidenceevidence at protein level
Length285
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesDDAH1

GO terms

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GOName
GO:0000052 citrulline metabolic process
GO:0003073 regulation of systemic arterial blood pressure
GO:0003824 catalytic activity
GO:0005829 cytosol
GO:0006525 arginine metabolic process
GO:0006527 arginine catabolic process
GO:0007263 nitric oxide mediated signal transduction
GO:0008285 negative regulation of cell population proliferation
GO:0016403 dimethylargininase activity
GO:0016597 amino acid binding
GO:0043116 negative regulation of vascular permeability
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding
GO:0050999 regulation of nitric-oxide synthase activity
GO:0070062 extracellular exosome
GO:1900038 negative regulation of cellular response to hypoxia

Subcellular Location

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Domains

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DomainNameCategoryType
IPR033197 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1FamilyFamily
IPR033199 Dimethylarginine dimethylaminohydrolaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00155 CitrullineDrugbanksmall molecule
DB00213 PantoprazoleDrugbanksmall molecule
DB00736 EsomeprazoleDrugbanksmall molecule
DB05351 DexlansoprazoleDrugbanksmall molecule

Interactions

4 interactions