Entity Details

Primary name SIX6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95475
EntryNameSIX6_HUMAN
FullNameHomeobox protein SIX6
TaxID9606
Evidenceevidence at protein level
Length246
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesSIX6

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007601 visual perception
GO:0009887 animal organ morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR031701 Homeobox protein SIX1, N-terminal SD domainDomainDomain
IPR032947 Homeobox protein SIX6FamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SIX6_HUMANTF2AY_HUMANBioGRID, IntAct20211142 details
SIX6_HUMANTLE1_HUMANBioGRID, HPRD12441302 details
SIX6_HUMANTLE5_HUMANBioGRID, HPRD12441302 details