Entity Details

Primary name OXSR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95747
EntryNameOXSR1_HUMAN
FullNameSerine/threonine-protein kinase OSR1
TaxID9606
Evidenceevidence at protein level
Length527
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesOXSR1

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006979 response to oxidative stress
GO:0007165 signal transduction
GO:0007231 osmosensory signaling pathway
GO:0010820 positive regulation of T cell chemotaxis
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0035556 intracellular signal transduction
GO:0038116 chemokine (C-C motif) ligand 21 signaling pathway
GO:0038146 chemokine (C-X-C motif) ligand 12 signaling pathway
GO:0042802 identical protein binding
GO:0046777 protein autophosphorylation
GO:0070062 extracellular exosome
GO:0071476 cellular hypotonic response
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1990869 cellular response to chemokine

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR024678 Serine/threonine-protein kinase OSR1/WNK, CCT domainDomainDomain
IPR028749 Serine/threonine-protein kinase OSR1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule