Entity Details

Primary name CALC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01258
EntryNameCALC_HUMAN
FullNameCalcitonin
TaxID9606
Evidenceevidence at protein level
Length141
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCALCA

GO terms

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GOName
GO:0001984 artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
GO:0002548 monocyte chemotaxis
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007566 embryo implantation
GO:0007568 aging
GO:0007631 feeding behavior
GO:0008016 regulation of heart contraction
GO:0009408 response to heat
GO:0030279 negative regulation of ossification
GO:0031716 calcitonin receptor binding
GO:0032147 activation of protein kinase activity
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0045779 negative regulation of bone resorption
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045986 negative regulation of smooth muscle contraction
GO:0048265 response to pain
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0071356 cellular response to tumor necrosis factor
GO:1990000 amyloid fibril formation
GO:1990090 cellular response to nerve growth factor stimulus

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001693 Calcitonin peptide-likeDomainDomain
IPR018360 Calcitonin, conserved siteSiteConserved site
IPR021116 Calcitonin/adrenomedullinFamilyFamily
IPR021117 Calcitonin-likeFamilyFamily
IPR021118 CalcitoninFamilyFamily

Diseases

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