Entity Details

Primary name HEMO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02790
EntryNameHEMO_HUMAN
FullNameHemopexin
TaxID9606
Evidenceevidence at protein level
Length462
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesHPX

GO terms

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GOName
GO:0002639 positive regulation of immunoglobulin production
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006879 cellular iron ion homeostasis
GO:0006898 receptor-mediated endocytosis
GO:0015232 heme transmembrane transporter activity
GO:0015886 heme transport
GO:0016032 viral process
GO:0020027 hemoglobin metabolic process
GO:0042168 heme metabolic process
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0046872 metal ion binding
GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071682 endocytic vesicle lumen
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000585 Hemopexin-like domainDomainDomain
IPR016358 HemopexinFamilyFamily
IPR018486 Hemopexin, conserved siteSiteConserved site
IPR018487 Hemopexin-like repeatsRepeatRepeat
IPR036375 Hemopexin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
HEMO_HUMANDHE3_HUMANBioGRID, IntAct21988832 details
HEMO_HUMANP63_HUMANBioGRID, IntAct21988832 details
HEMO_HUMANHS90A_HUMANBioGRID31273033 details