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Entity Details
Primary name
C4BPA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P04003
EntryName
C4BPA_HUMAN
FullName
C4b-binding protein alpha chain
TaxID
9606
Evidence
evidence at protein level
Length
597
SequenceStatus
complete
DateCreated
1986-10-23
DateModified
2021-06-02
Ontological Relatives
Genes
C4BPA
GO terms
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GO
Name
GO:0003723
RNA binding
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005886
plasma membrane
GO:0006958
complement activation, classical pathway
GO:0009609
response to symbiotic bacterium
GO:0030449
regulation of complement activation
GO:0045087
innate immune response
GO:0045732
positive regulation of protein catabolic process
GO:0045959
negative regulation of complement activation, classical pathway
GO:0072562
blood microparticle
GO:1903027
regulation of opsonization
Subcellular Location
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Subcellular Location
Secreted
Domains
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Domain
Name
Category
Type
IPR000436
Sushi/SCR/CCP domain
Domain
Domain
IPR035976
Sushi/SCR/CCP superfamily
Family
Homologous superfamily
IPR040514
C4b-binding protein alpha, oligomerization domain
Domain
Domain
Diseases
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Drugs
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Drug
Name
Source
Type
DB01593
Zinc
Drugbank
small molecule
DB09130
Copper
Drugbank
small molecule
DB14487
Zinc acetate
Drugbank
small molecule
DB14533
Zinc chloride
Drugbank
small molecule
DB14548
Zinc sulfate, unspecified form
Drugbank
small molecule
Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
C4BPA_HUMAN
GTF2I_HUMAN
BioGRID, IntAct
21988832
details
C4BPA_HUMAN
FXYD6_HUMAN
BioGRID, IntAct
21988832
details
C4BPA_HUMAN
LBP_HUMAN
BioGRID, IntAct
21988832
details
C4BPA_HUMAN
SMRD1_HUMAN
BioGRID, IntAct
21988832
details
C4BPA_HUMAN
GIT2_HUMAN
BioGRID, IntAct
21988832
details
C4BPA_HUMAN
HS90A_HUMAN
BioGRID
31273033
details
C4BPA_HUMAN
SAMP_HUMAN
BioGRID, HPRD
12100475
7592941
details
C4BPA_HUMAN
LRP1_HUMAN
HPRD
11705989
details
C4BPA_HUMAN
PROS_HUMAN
HPRD
10744423
1534488
1833851
details
C4BPA_HUMAN
BMPR2_HUMAN
HPRD
15188402
details
C4BPA_HUMAN
CO4A_HUMAN
HPRD
12893820
details
C4BPA_HUMAN
CO4B_HUMAN
HPRD
12893820
details
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