Entity Details

Primary name PERM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05164
EntryNamePERM_HUMAN
FullNameMyeloperoxidase
TaxID9606
Evidenceevidence at protein level
Length745
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesMPO

GO terms

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GOName
GO:0001878 response to yeast
GO:0002149 hypochlorous acid biosynthetic process
GO:0002679 respiratory burst involved in defense response
GO:0003682 chromatin binding
GO:0004601 peroxidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0006952 defense response
GO:0006979 response to oxidative stress
GO:0007568 aging
GO:0008201 heparin binding
GO:0009612 response to mechanical stimulus
GO:0019430 removal of superoxide radicals
GO:0020037 heme binding
GO:0030141 secretory granule
GO:0032094 response to food
GO:0032496 response to lipopolysaccharide
GO:0034374 low-density lipoprotein particle remodeling
GO:0035578 azurophil granule lumen
GO:0042582 azurophil granule
GO:0042742 defense response to bacterium
GO:0042744 hydrogen peroxide catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0045454 cell redox homeostasis
GO:0046872 metal ion binding
GO:0050832 defense response to fungus
GO:0070062 extracellular exosome
GO:0097013 phagocytic vesicle lumen
GO:1990268 response to gold nanoparticle

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR010255 Haem peroxidase superfamilyFamilyHomologous superfamily
IPR019791 Haem peroxidase, animal-typeFamilyFamily
IPR029609 MyeloperoxidaseFamilyFamily
IPR037120 Haem peroxidase domain superfamily, animal typeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00006 BivalirudinDrugbanksmall molecule
DB00104 OctreotideSwissprotsmall molecule
DB00208 TiclopidineDrugbanksmall molecule
DB00233 Aminosalicylic acidDrugbanksmall molecule
DB00244 MesalazineDrugbanksmall molecule
DB00250 DapsoneDrugbanksmall molecule
DB00461 NabumetoneDrugbanksmall molecule
DB00500 TolmetinDrugbanksmall molecule
DB00515 CisplatinDrugbanksmall molecule
DB00526 OxaliplatinSwissprotsmall molecule
DB00535 CefdinirDrugbanksmall molecule
DB00550 PropylthiouracilDrugbanksmall molecule
DB00583 LevocarnitineDrugbanksmall molecule
DB00833 CefaclorDrugbanksmall molecule
DB00847 CysteamineDrugbanksmall molecule
DB00958 CarboplatinSwissprotsmall molecule
DB01065 MelatoninDrugbanksmall molecule
DB01225 EnoxaparinDrugbanksmall molecule
DB02300 CalcipotriolDrugbanksmall molecule
DB04821 NomifensineDrugbanksmall molecule
DB04827 UrethaneSwissprotsmall molecule
DB05161 ElafinDrugbanksmall molecule
DB06111 AB192Swissprotsmall molecule
DB06468 CariporideDrugbanksmall molecule
DB06774 CapsaicinDrugbanksmall molecule
DB06823 TioproninSwissprotsmall molecule