Entity Details

Primary name MGST1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10620
EntryNameMGST1_HUMAN
FullNameMicrosomal glutathione S-transferase 1
TaxID9606
Evidenceevidence at protein level
Length155
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMGST1

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005778 peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0010243 response to organonitrogen compound
GO:0016021 integral component of membrane
GO:0032496 response to lipopolysaccharide
GO:0033327 Leydig cell differentiation
GO:0034635 glutathione transport
GO:0035577 azurophil granule membrane
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043295 glutathione binding
GO:0043312 neutrophil degranulation
GO:0045177 apical part of cell
GO:0046222 aflatoxin metabolic process
GO:0071449 cellular response to lipid hydroperoxide
GO:1901687 glutathione derivative biosynthetic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) proteinFamilyFamily
IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamilyFamilyHomologous superfamily
IPR040162 Microsomal glutathione S-transferase 1-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB03310 Glutathione disulfideDrugbanksmall molecule