Entity Details

Primary name GILT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13284
EntryNameGILT_HUMAN
FullNameGamma-interferon-inducible lysosomal thiol reductase
TaxID9606
Evidenceevidence at protein level
Length250
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesIFI30

GO terms

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GOName
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0005829 cytosol
GO:0016491 oxidoreductase activity
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030054 cell junction
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0048147 negative regulation of fibroblast proliferation
GO:0050821 protein stabilization
GO:0060333 interferon-gamma-mediated signaling pathway

Subcellular Location

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Subcellular Location
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR004911 Gamma interferon inducible lysosomal thiol reductase GILTFamilyFamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
GILT_HUMANNT2NA_HUMANBioGRID, IntAct25416956 details
GILT_HUMANKR412_HUMANBioGRID, IntAct25416956 details
GILT_HUMANTGM1_HUMANBioGRID, IntAct32296183 details
GILT_HUMANNT2NC_HUMANBioGRID25416956 details