Entity Details

Primary name CEAM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13688
EntryNameCEAM1_HUMAN
FullNameCarcinoembryonic antigen-related cell adhesion molecule 1
TaxID9606
Evidenceevidence at protein level
Length526
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesCEACAM1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001558 regulation of cell growth
GO:0001568 blood vessel development
GO:0001915 negative regulation of T cell mediated cytotoxicity
GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0003779 actin binding
GO:0005516 calmodulin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0006469 negative regulation of protein kinase activity
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007229 integrin-mediated signaling pathway
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010594 regulation of endothelial cell migration
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0015125 bile acid transmembrane transporter activity
GO:0015721 bile acid and bile salt transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016477 cell migration
GO:0019900 kinase binding
GO:0019903 protein phosphatase binding
GO:0030054 cell junction
GO:0030334 regulation of cell migration
GO:0030658 transport vesicle membrane
GO:0030853 negative regulation of granulocyte differentiation
GO:0031005 filamin binding
GO:0031528 microvillus membrane
GO:0032692 negative regulation of interleukin-1 production
GO:0032869 cellular response to insulin stimulus
GO:0035579 specific granule membrane
GO:0035726 common myeloid progenitor cell proliferation
GO:0038016 insulin receptor internalization
GO:0038158 granulocyte colony-stimulating factor signaling pathway
GO:0042058 regulation of epidermal growth factor receptor signaling pathway
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043116 negative regulation of vascular permeability
GO:0043312 neutrophil degranulation
GO:0043318 negative regulation of cytotoxic T cell degranulation
GO:0044319 wound healing, spreading of cells
GO:0045601 regulation of endothelial cell differentiation
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0046983 protein dimerization activity
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050900 leukocyte migration
GO:0051055 negative regulation of lipid biosynthetic process
GO:0060312 regulation of blood vessel remodeling
GO:0070062 extracellular exosome
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0070821 tertiary granule membrane
GO:0090331 negative regulation of platelet aggregation
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:1901143 insulin catabolic process
GO:1903385 regulation of homophilic cell adhesion
GO:1903670 regulation of sprouting angiogenesis
GO:1990782 protein tyrosine kinase binding
GO:2000346 negative regulation of hepatocyte proliferation
GO:2001214 positive regulation of vasculogenesis

Subcellular Location

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Subcellular Location
Apical cell membrane
Basal cell membrane
Cell junction
Cell membrane
Cell projection
Cytoplasmic vesicle
Lateral cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00113 Technetium Tc-99m arcitumomabDrugbankbiotech