Entity Details

Primary name B4GT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15291
EntryNameB4GT1_HUMAN
FullNameBeta-1,4-galactosyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length398
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesB4GALT1

GO terms

Show/Hide Table
GOName
GO:0000138 Golgi trans cisterna
GO:0000139 Golgi membrane
GO:0002064 epithelial cell development
GO:0002526 acute inflammatory response
GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0003945 N-acetyllactosamine synthase activity
GO:0004461 lactose synthase activity
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005989 lactose biosynthetic process
GO:0006012 galactose metabolic process
GO:0006487 protein N-linked glycosylation
GO:0007155 cell adhesion
GO:0007339 binding of sperm to zona pellucida
GO:0007341 penetration of zona pellucida
GO:0008092 cytoskeletal protein binding
GO:0008285 negative regulation of cell population proliferation
GO:0008378 galactosyltransferase activity
GO:0009312 oligosaccharide biosynthetic process
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0018146 keratan sulfate biosynthetic process
GO:0030057 desmosome
GO:0030145 manganese ion binding
GO:0030175 filopodium
GO:0030198 extracellular matrix organization
GO:0030667 secretory granule membrane
GO:0031526 brush border membrane
GO:0032580 Golgi cisterna membrane
GO:0035250 UDP-galactosyltransferase activity
GO:0035577 azurophil granule membrane
GO:0042802 identical protein binding
GO:0043014 alpha-tubulin binding
GO:0043065 positive regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0045136 development of secondary sexual characteristics
GO:0048487 beta-tubulin binding
GO:0050900 leukocyte migration
GO:0060046 regulation of acrosome reaction
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0060055 angiogenesis involved in wound healing
GO:0070062 extracellular exosome
GO:0070085 glycosylation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cell projection
Cell surface
Golgi apparatus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR003859 Beta-1,4-galactosyltransferaseFamilyFamily
IPR027791 Galactosyltransferase, C-terminalDomainDomain
IPR027995 Galactosyltransferase, N-terminalDomainDomain
IPR029044 Nucleotide-diphospho-sugar transferasesFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00141 N-AcetylglucosamineDrugbanksmall molecule
DB02696 6-Aminohexyl-uridine-C1,5'-diphosphateDrugbanksmall molecule
DB03013 N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamineDrugbanksmall molecule
DB03501 Galactose-uridine-5'-diphosphateDrugbanksmall molecule
DB03685 Uridine monophosphateDrugbanksmall molecule
DB03814 2-(N-morpholino)ethanesulfonic acidDrugbanksmall molecule