Entity Details

Primary name HXB8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17481
EntryNameHXB8_HUMAN
FullNameHomeobox protein Hox-B8
TaxID9606
Evidenceevidence at protein level
Length243
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesHOXB8

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007625 grooming behavior
GO:0008344 adult locomotory behavior
GO:0009952 anterior/posterior pattern specification
GO:0019233 sensory perception of pain
GO:0021516 dorsal spinal cord development
GO:0045638 negative regulation of myeloid cell differentiation
GO:0048704 embryonic skeletal system morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

5 interactions