Entity Details

Primary name ITIH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19827
EntryNameITIH1_HUMAN
FullNameInter-alpha-trypsin inhibitor heavy chain H1
TaxID9606
Evidenceevidence at protein level
Length911
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesITIH1

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0030212 hyaluronan metabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR010600 Inter-alpha-trypsin inhibitor heavy chain, C-terminalDomainDomain
IPR013694 VIT domainDomainDomain
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09338 MersalylDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ITIH1_HUMANPK3CA_HUMANBioGRID, IntAct18624398 details
ITIH1_HUMANSOX4_HUMANBioGRID25969425 details
ITIH1_HUMANHS90A_HUMANBioGRID31273033 details