Entity Details

Primary name MRC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22897
EntryNameMRC1_HUMAN
FullNameMacrophage mannose receptor 1
TaxID9606
Evidenceevidence at protein level
Length1456
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesMRC1

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0005537 mannose binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0038023 signaling receptor activity
GO:0038024 cargo receptor activity
GO:0052031 modulation by symbiont of host defense response
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0071353 cellular response to interleukin-4

Subcellular Location

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Subcellular Location
Cell membrane
Endosome membrane

Domains

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DomainNameCategoryType
IPR000562 Fibronectin type II domainDomainDomain
IPR000772 Ricin B, lectin domainDomainDomain
IPR001304 C-type lectin-likeDomainDomain
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR035992 Ricin B-like lectinsFamilyHomologous superfamily
IPR036943 Fibronectin type II domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09266 Technetium Tc-99m tilmanoceptDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MRC1_HUMANCHK2_HUMANHPRD11715017 details
MRC1_HUMANATP4A_HUMANBioGRID17255364 details