Entity Details

Primary name PTPRG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23470
EntryNamePTPRG_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase gamma
TaxID9606
Evidenceevidence at protein level
Length1445
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRG

GO terms

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GOName
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005887 integral component of plasma membrane
GO:0006470 protein dephosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007420 brain development
GO:0010633 negative regulation of epithelial cell migration
GO:0010977 negative regulation of neuron projection development
GO:0042802 identical protein binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR001148 Alpha carbonic anhydrase domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036398 Alpha carbonic anhydrase domain superfamilyFamilyHomologous superfamily
IPR041887 Receptor-type tyrosine-protein phosphatase, carbonic anhydrase domainDomainDomain

Diseases

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