Entity Details

Primary name ACKR3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP25106
EntryNameACKR3_HUMAN
FullNameAtypical chemokine receptor 3
TaxID9606
Evidenceevidence at protein level
Length362
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesACKR3

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0005044 scavenger receptor activity
GO:0005634 nucleus
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008285 negative regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0015026 coreceptor activity
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0019958 C-X-C chemokine binding
GO:0031623 receptor internalization
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0055037 recycling endosome
GO:0060326 cell chemotaxis
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1905322 positive regulation of mesenchymal stem cell migration

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Early endosome
Recycling endosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001416 Atypical chemokine receptor 3FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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