Entity Details

Primary name NKG2C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26717
EntryNameNKG2C_HUMAN
FullNameNKG2-C type II integral membrane protein
TaxID9606
Evidenceevidence at protein level
Length231
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesKLRC2

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002228 natural killer cell mediated immunity
GO:0002250 adaptive immune response
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0023024 MHC class I protein complex binding
GO:0030246 carbohydrate binding
GO:0043235 receptor complex
GO:0043323 positive regulation of natural killer cell degranulation
GO:0045087 innate immune response
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0062081 activating MHC class Ib receptor activity
GO:1990405 protein antigen binding

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR033992 Natural killer cell receptor-like, C-type lectin-like domainDomainDomain

Diseases

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Interactions

4 interactions